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How to Treat Hyperhidrosis With Botox and Morpheus8

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Excessive sweating can be uncomfortable, inconvenient, and (for many people) deeply embarrassing. Whether it’s underarm sweat stains, clammy palms, or facial perspiration that appears out of nowhere, hyperhidrosis can interfere with your daily life and confidence.

But here’s the good news: There are safe, non-surgical treatments that can help stop excessive sweating for months at a time. Two of the most effective options are Botox® injections and Morpheus8 RF microneedling, both of which target overactive sweat glands at the source.

Let’s explore what hyperhidrosis is, what causes it, and how these advanced treatments work together to give you long-lasting relief from unwanted perspiration.

What Is Hyperhidrosis?

Hyperhidrosis is a medical condition where your sweat glands produce more sweat than your body needs to regulate temperature. Unlike normal sweating, which happens in response to heat, stress, or exercise, hyperhidrosis can cause excessive sweating even when you’re cool or resting.

This condition can affect:

  • Underarms (axillary hyperhidrosis)
  • Palms of the hands
  • Soles of the feet
  • Scalp or forehead
  • Face and neck

While sweating itself is normal, hyperhidrosis is different. It’s persistent, excessive, and can disrupt both physical comfort and emotional wellbeing.

What Causes Excessive Sweating?

The cause of hyperhidrosis depends on which type you have.

1. Primary Focal Hyperhidrosis

This is the most common form. It’s usually genetic and localized to specific areas like your underarms, hands, feet, or face. In this type, the nerves that control sweating are overactive, triggering perspiration even when it’s not needed.

2. Secondary Generalized Hyperhidrosis

This form is caused by an underlying medical condition or certain medications. It can affect the entire body and may be related to:

  • Hyperthyroidism (overactive thyroid)
  • Diabetes
  • Menopause
  • Obesity
  • Infections such as tuberculosis or HIV
  • Neurological disorders (e.g., Parkinson’s disease)
  • Some cancer or heart conditions

If your sweating started suddenly, affects your whole body, or happens while you sleep, your provider may recommend blood tests to rule out secondary causes before treatment.

How Botox Can Help Reduce Sweating

You may already know Botox® as a cosmetic treatment for fine lines and wrinkles. But it’s also a powerful medical therapy for controlling hyperhidrosis, and it’s been FDA-approved for treating excessive underarm sweating since 2004.

Here’s how it works:

How Botox Treats Sweat Glands

When injected into the skin, Botox temporarily blocks the chemical signals (acetylcholine) that stimulate your sweat glands. Without this signal, the sweat glands stop overproducing sweat — reducing moisture dramatically in the treated area.

Treatment Areas

  • Underarms: The most common and FDA-approved site for hyperhidrosis treatment
  • Palms: Effective for hand sweating (though can cause mild, temporary weakness)
  • Feet: Helps reduce plantar sweating
  • Face and scalp: Great for those who experience facial perspiration

The Procedure

  • The skin is cleansed and sometimes numbed for comfort.
  • A series of small Botox injections are placed just below the surface of the skin in a grid-like pattern.
  • The process takes 15–30 minutes, depending on the area.

Most patients resume their normal activities immediately afterward. It’s quick, simple, and effective.

When You’ll See Results

You’ll start noticing results within 3–5 days, with full dryness achieved in about two weeks.

How Long It Lasts

Results typically last 6 to 9 months, and many patients return for maintenance treatments twice a year. Over time, you may even need fewer injections as your sweat glands become less overactive.

The Science Behind Botox for Sweat Reduction

Each Botox injection blocks the nerve endings that control sweat gland activation, effectively “switching off” sweat production in targeted areas. This doesn’t affect your body’s ability to regulate temperature — it simply reduces excessive sweating in specific spots.

Research shows that Botox can reduce sweating by up to 80–90% in treated areas. Most patients report a huge improvement in confidence, comfort, and quality of life.

Introducing Morpheus8: A Breakthrough in Sweat Gland Reduction

While Botox is excellent for temporarily stopping sweat, Morpheus8 RF microneedling offers another exciting option for those seeking longer-lasting improvement in sweat control.

What Is Morpheus8?

Morpheus8 is an advanced treatment that combines microneedling with radiofrequency (RF) energy to target the skin’s deeper layers. The RF heat stimulates collagen production and remodels tissues — but it also has an exciting secondary benefit: it can disrupt overactive sweat glands.

This makes Morpheus8 a powerful, non-invasive way to help reduce sweat production and improve skin tone and texture at the same time.

How Morpheus8 Helps Control Sweating

When Morpheus8’s microneedles deliver controlled RF energy into the skin, the heat energy damages overactive sweat glands, minimizing their activity over time.

Here’s why it works so well:

  • Targets sweat glands directly without surgery or medication
  • Reduces pore size and improves overall skin quality
  • Promotes collagen and elastin renewal for firmer, smoother skin
  • Provides lasting reduction in sweat production with minimal downtime

Morpheus8 can be used for underarms, palms, forehead, and even body areas prone to sweat or oil buildup.

Comparing Botox vs. Morpheus8 for Hyperhidrosis

Both treatments are effective, safe, and non-invasive — but they work in different ways and can even complement each other.

Botox

Morpheus8 RF

Mechanism

Temporarily blocks sweat gland nerve signals

Uses radiofrequency energy to heat and disable sweat glands

Treatment Time

15–30 minutes

30–45 minutes

Results Appear

Within 3–5 days

Gradually over several weeks

Duration of Results

6–9 months

Up to 12 months or longer

Downtime

None

Mild redness for 1–2 days

Ideal For

Quick relief from localized sweating (e.g., underarms)

Long-term sweat reduction and skin rejuvenation

Some patients choose Botox for immediate results and then follow up with Morpheus8 sessions for extended sweat control and skin tightening benefits.

What to Expect During Treatment at Glow Aesthetic Center

Step 1: Consultation

Your provider will assess your symptoms, medical history, and treatment goals. Depending on your needs, they may recommend Botox, Morpheus8, or a combination of both for optimal results.

Step 2: Preparation

The treatment area is cleansed, and a topical numbing cream is applied for comfort.

Step 3: Procedure

  • For Botox: A series of small injections are performed in the targeted areas.
  • For Morpheus8: The handheld device delivers microneedling and radiofrequency energy simultaneously to the skin.

Step 4: Recovery and Results

Both treatments are non-surgical and require no downtime. You might experience slight redness, swelling, or warmth for a day or two, but you can return to normal activities right away.

The Benefits of Treating Hyperhidrosis

Treating excessive sweating is about more than just comfort — it can significantly improve your daily life and confidence.

1. Boosted Confidence

Say goodbye to sweat stains, damp palms, and constant discomfort.

2. Improved Hygiene

Reducing sweat lowers bacterial buildup, odor, and irritation.

3. Wardrobe Freedom

Wear lighter colors and fabrics without fear of visible sweat marks.

4. Non-Surgical and Safe

Both Botox and Morpheus8 are FDA-approved, minimally invasive, and performed in-office.

5. Fast, Lasting Relief

You’ll enjoy noticeable dryness within days (with Botox) or gradual, long-term improvement (with Morpheus8).

How Long Do the Results Last?

  • Botox: 6–9 months
  • Morpheus8: 9–12 months, with cumulative improvements over multiple sessions

Many patients schedule maintenance sessions annually or semiannually to keep sweat production under control.

Are There Any Risks or Side Effects?

Both treatments are extremely safe when performed by trained professionals.

Possible side effects may include:

  • Mild redness or swelling
  • Temporary tenderness
  • Rarely, slight bruising or minor sensitivity at injection sites

With Morpheus8, there may be light flaking or warmth for a few days as the skin renews. Your provider will give you personalized aftercare instructions to keep the area clean and comfortable.

Am I a Good Candidate?

You may be a great candidate if you:

  • Sweat excessively even in cool conditions
  • Have tried clinical-strength antiperspirants or medications without success
  • Want a non-surgical, lasting solution
  • Are in good overall health

During your consultation at Glow Aesthetic Center, our specialists will design a treatment plan that suits your symptoms, lifestyle, and comfort level.

Combining Botox and Morpheus8 for Best Results

Many patients see the greatest improvement when both treatments are combined. Botox offers fast-acting relief, while Morpheus8 provides long-term improvement by reducing gland activity and rejuvenating the skin.

This dual approach can extend the duration of results and offer more comprehensive sweat control, especially for those with stubborn hyperhidrosis.

Experience Sweat-Free Confidence With Glow Aesthetic Center

If excessive sweating is affecting your daily life, there’s no reason to continue struggling in silence. Both Botox and Morpheus8 offer safe, proven ways to restore your confidence and comfort.

At Glow Aesthetic Center, our experienced medical team specializes in sweat reduction treatments that deliver real results. We combine medical expertise with advanced technology to help you live confidently — dry, fresh, and worry-free.

FAQs

What areas can be treated for hyperhidrosis with Botox or Morpheus8?

Both treatments can be used for underarms, palms, feet, face, scalp, and other localized areas where sweat glands are overactive.

How soon will I notice a reduction in sweating after treatment?

Botox typically begins working within a few days with full dryness by two weeks. Morpheus8 results appear gradually over several weeks as sweat gland activity decreases.

Can Botox and Morpheus8 be combined for better results?

Yes. Many patients use Botox for quick improvement and Morpheus8 for longer-lasting sweat reduction. The combined approach can extend overall effectiveness.

Is there downtime after treating hyperhidrosis with Botox or Morpheus8?

There is no downtime with Botox and only mild, temporary redness with Morpheus8. Most patients return to daily activities immediately after both treatments.

How long do results typically last?

Botox usually controls sweating for six to nine months, while Morpheus8 can offer benefits for nine to twelve months or longer. Maintenance sessions help sustain dryness.

 

Woman adjusting a beige dress with a white bow detail, demonstrating how to properly fit and style the garment. Background features a textured white wall, highlighting the focus on fashion and styling tips.
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Becoming a VIP Member at Glow Aesthetic Centers means unlocking exclusive perks designed to help you look and feel your best year-round. VIP members enjoy special savings on treatments and products, priority access to appointments and promotions, and members-only offers curated just for you. It’s our way of rewarding your commitment to self-care with elevated benefits, personalized experiences, and exceptional value every visit.

VIP membership promotional image highlighting benefits such as free microneedling, 10% off all products, and 10% off all treatments at Glow Med Spa Encino. The image features a person receiving a microneedling treatment, a selection of skincare products, and a relaxing facial treatment.

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VIP membership promotional image highlighting benefits such as free microneedling, 10% off all products, and 10% off all treatments at Glow Med Spa Encino. The image features a person receiving a microneedling treatment, a selection of skincare products, and a relaxing facial treatment.

Become A VIP Member!

Becoming a VIP Member at Glow Aesthetic Centers means unlocking exclusive perks designed to help you look and feel your best year-round. VIP members enjoy special savings on treatments and products, priority access to appointments and promotions, and members-only offers curated just for you. It’s our way of rewarding your commitment to self-care with elevated benefits, personalized experiences, and exceptional value every visit.

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