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How GLP-1 Works

Woman measuring her waist with a yellow tape measure, showcasing fitness and body measurement in a bright, neutral background.

If you’ve heard about popular medications like semaglutide, you’ve already encountered GLP-1 — one of the most talked-about breakthroughs in modern metabolic health. But what exactly is GLP-1, and how does it work inside your body to promote weight loss, stabilize blood sugar, and support long-term wellness?

At Glow Aesthetic Center, our team uses advanced, medically supervised GLP-1 treatments to help patients achieve sustainable weight management and improved metabolic balance — safely and effectively.

This guide explains what GLP-1 is, how it functions in the body, and why it’s transforming the way we approach weight loss and overall health.

What Is GLP-1?

GLP-1, short for glucagon-like peptide-1, is a naturally occurring hormone your body produces in the small intestine after eating. It plays a vital role in regulating blood sugar, appetite, and digestion.

In simple terms, GLP-1 is one of the body’s “metabolic messengers.” It signals to the brain and other organs that food has been consumed, helping manage how you process energy and when you feel full.

Scientists have long studied GLP-1 for its ability to balance glucose levels in people with diabetes. Over the past decade, medical research revealed another remarkable effect: GLP-1 also reduces appetite and promotes gradual, sustained weight loss — making it one of the most significant medical advancements in obesity treatment.

How GLP-1 Works in the Body

To understand how GLP-1 medications work, it’s helpful to look at what this hormone does naturally inside your body.

When you eat, GLP-1 is released from your intestines into your bloodstream. It acts on multiple systems simultaneously to help maintain energy balance.

Here’s how:

1. Slows Gastric Emptying

GLP-1 slows the rate at which your stomach empties food into the small intestine. This means you feel fuller for longer after eating, which naturally helps reduce portion sizes and snacking.

2. Regulates Appetite in the Brain

GLP-1 receptors are found in the hypothalamus (the part of the brain that controls hunger and satiety). When activated, these receptors send signals that suppress appetite and reduce cravings.

As a result, you’re less likely to overeat or experience the constant hunger that often sabotages weight loss efforts.

3. Enhances Insulin Secretion

GLP-1 boosts insulin production in response to glucose (sugar) in the bloodstream. Insulin helps move sugar from your blood into your cells, where it’s used for energy.

By improving insulin response, GLP-1 helps keep blood sugar levels stable after meals.

4. Reduces Glucagon Production

Glucagon is a hormone that raises blood sugar levels by signaling the liver to release stored glucose. GLP-1 suppresses glucagon, helping to prevent blood sugar spikes.

5. Supports Cardiovascular and Metabolic Health

Research shows GLP-1 can improve blood pressure, cholesterol, and inflammation, supporting better heart health in addition to metabolic function.

Together, these effects make GLP-1 a cornerstone of modern weight management and metabolic therapy.

GLP-1 Medications: What They Are and How They Work

GLP-1–based medications mimic your body’s natural hormone but in a longer-lasting form. They bind to GLP-1 receptors, activating the same pathways that regulate appetite, digestion, and insulin response with greater consistency.

These medications are typically administered as a once-weekly injection, making them both convenient and effective.

At Glow Aesthetic Center, we use medically supervised GLP-1 treatments as part of a holistic program that includes nutrition guidance, lifestyle support, and ongoing care, ensuring patients experience safe, sustainable results.

The Benefits of GLP-1 Treatments

The results of GLP-1 therapy go far beyond the number on the scale. By addressing multiple pathways in the body, these medications offer comprehensive health benefits:

1. Effective Weight Loss

GLP-1 treatments help patients lose an average of 10–15% of their body weight over several months, depending on the dosage and consistency of use.

This level of weight loss can significantly reduce the risk of diabetes, heart disease, and other chronic conditions.

2. Better Appetite Control

By improving how your body regulates hunger and fullness, GLP-1 helps you develop healthier eating habits without extreme dieting or deprivation.

3. Improved Blood Sugar Regulation

GLP-1 treatments stabilize glucose levels, reducing insulin resistance and improving metabolic efficiency — even in people without diabetes.

4. Enhanced Cardiovascular Health

Clinical studies show that GLP-1 therapies can lower blood pressure and cholesterol, contributing to better heart health.

5. More Energy and Mental Clarity

As blood sugar and metabolic processes stabilize, many patients report increased energy, improved focus, and a better overall sense of well-being.

GLP-1 and the Science of Sustainable Weight Loss

Unlike traditional weight loss methods that rely on calorie restriction alone, GLP-1 medications work at the hormonal level, targeting the root causes of weight gain.

Obesity is not simply about willpower — it’s a complex condition influenced by hormones, metabolism, and genetics. By improving how your body processes energy and signals hunger, GLP-1 treatments make it easier to maintain a calorie deficit naturally.

What’s more, the gradual pace of weight loss helps protect lean muscle mass, maintain energy levels, and reduce the risk of rebound weight gain once the treatment plan stabilizes.

What to Expect During GLP-1 Treatment

At Glow Aesthetic Center, GLP-1 therapy is customized for each patient through medical evaluation and ongoing support.

Here’s what the process looks like:

1. Consultation

Your provider reviews your health history, weight management goals, and any previous treatments to determine if GLP-1 therapy is right for you.

2. Treatment Plan

A personalized dosing schedule is developed, starting with a low dose to minimize side effects while your body adjusts.

3. Regular Follow-Ups

Your provider monitors progress, adjusts dosage as needed, and supports you with nutrition, hydration, and lifestyle tips to maximize results.

4. Visible Results

Most patients begin noticing reduced appetite and gradual weight loss within the first 4–6 weeks, with continued improvements over several months.

Potential Side Effects

GLP-1 medications are generally safe and well-tolerated when prescribed and monitored by a medical professional.

Common temporary side effects may include:

  • Mild nausea or bloating
  • Decreased appetite
  • Constipation or diarrhea
  • Occasional fatigue

These effects usually diminish as your body adjusts to the medication. Staying hydrated and eating smaller, balanced meals can help minimize discomfort.

Your Glow provider will closely monitor your progress to ensure optimal safety and comfort throughout your treatment.

Who Is a Good Candidate for GLP-1 Treatment?

You may be a good candidate if you:

  • Struggle with weight loss despite diet and exercise
  • Have a BMI of 27 or higher (with or without weight-related health concerns)
  • Want to reduce your risk of diabetes or heart disease
  • Experience challenges with appetite control or cravings
  • Prefer a non-surgical, medically supervised approach

GLP-1 therapy is not recommended for individuals with certain thyroid or gastrointestinal conditions, or those who are pregnant or breastfeeding.

Your consultation at Glow Aesthetic Center ensures your treatment plan is personalized and medically appropriate.

Final Thoughts

GLP-1 represents one of the most powerful and scientifically advanced tools for modern weight management and metabolic health.

By mimicking your body’s natural hormones, GLP-1 helps regulate appetite, stabilize blood sugar, and improve overall energy balance all while supporting sustainable, healthy weight loss.

If you’re ready to take a science-backed approach to your health and wellness, the medical team at Glow Aesthetic Center can help you determine if GLP-1 therapy is right for you.

Frequently Asked Questions

What does GLP-1 stand for?

GLP-1 stands for glucagon-like peptide-1, a hormone that regulates appetite, blood sugar, and metabolism.

How long does it take to see results?

Most patients begin to notice appetite control and weight loss within 4–6 weeks, with continued progress over several months.

Do I need to follow a diet with GLP-1 therapy?

While no strict diet is required, following a balanced, nutrient-rich meal plan enhances results and overall well-being.

Is GLP-1 safe for non-diabetic patients?

Yes. GLP-1 medications are safe and effective for individuals seeking weight loss or metabolic improvement, even without diabetes.

Will I regain weight if I stop taking it?

Some patients may regain weight if they return to old habits. Ongoing lifestyle changes and maintenance support help sustain results.

Are GLP-1 injections painful?

Not at all. The injections use a very fine needle and are typically well-tolerated.

Can GLP-1 therapy be combined with other treatments?

Yes. Your provider can combine GLP-1 therapy with vitamin IV treatments, hormone support, or other wellness therapies for a comprehensive plan.

Woman measuring her waist with a yellow tape measure, showcasing fitness and body measurement in a bright, neutral background.
Current Promotions

Glow Aesthetic Center is celebrating its 35th Anniversary with our biggest December specials ever at both Encino and Thousand Oaks locations. Enjoy incredible pricing on injectables like Xeomin and Botox at $10.50/unit, Dysport at $2.99/unit, Restylane fillers at $699/syringe, and Sculptra or Radiesse at $599/vial. Take advantage of treatment deals including VI Peels from $299, Microneedling at $299, Vampire Facials at $550, Hydrafacial + LED for $199, and EZ Gel at $960/area. We’re also offering discounted Kybella, Thermismooth, PRP O-Shot, PRP Hair Injections, NAD+ shots, and monthly Semaglutide. Plus, save on packages like 3 PRP/Vampire Facials for $1400 or 3 Microneedling sessions for $750. All month long—celebrate with us and glow into the new year! – Purchase Now!

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Saturday: Closed

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35th Anniversary Specials

Glow Aesthetic Center is celebrating 35 years with major December savings at both our Encino and Thousand Oaks locations, featuring discounted injectables like Xeomin and Botox at $10.50/unit, Dysport at $2.99/unit, and Restylane fillers at $699/syringe. Patients can also enjoy treatment specials including VI Peels from $299, Microneedling at $299, Hydrafacial + LED for $199, Vampire Facials at $550, and premium options like Sculptra, Radiesse, PRP, NAD+, EZ Gel, and Semaglutide at reduced pricing. Plus, we’re offering exclusive holiday packages—including 3 PRP/Vampire Facials for $1400 and 3 Microneedling sessions for $750—so you can look and feel your best all season long.

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