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What Dermal Filler Lasts the Longest?

Aesthetic treatment procedure showing a woman receiving an injection for facial enhancement, performed by a professional in blue gloves. The setting is a clean, clinical environment, emphasizing safety and expertise in cosmetic procedures.

Dermal fillers have become one of the most popular cosmetic treatments in the United States for restoring lost volume, softening wrinkles, and enhancing facial features. At Glow Aesthetic Center in Encino, we see patients every day who want natural-looking results without the downtime of surgery. A common question many patients ask during their consultation is: “Which dermal filler lasts the longest?”

The answer depends on several factors, including the specific filler used, where it is placed, and your body’s natural response. Both Juvéderm® and Restylane® offer excellent long-lasting fillers, each formulated for different areas of the face. While some fillers may last six months, others can last up to two years or more.

This blog will explain the different dermal filler options available at Glow Aesthetic Center, how long each typically lasts, and what you can expect from your treatment.

Understanding Dermal Fillers

Before diving into longevity, it’s helpful to understand what dermal fillers are and how they work.

Dermal fillers are injectable gels designed to replace lost volume, smooth out facial lines, and enhance features like lips and cheeks. Most fillers available today are made from hyaluronic acid (HA), a naturally occurring substance in the body that helps retain moisture and keep skin plump. Over time, our natural supply of HA diminishes, contributing to wrinkles, folds, and volume loss.

When HA-based fillers like Juvéderm or Restylane are injected, they restore fullness and hydration to targeted areas. Since hyaluronic acid is gradually broken down by the body, the results are temporary but can be maintained with repeat treatments.

Factors That Influence How Long Fillers Last

No two patients metabolize fillers exactly the same way, so results can vary. The following factors play a role in how long dermal fillers last:

  • Filler type and formulation: Some fillers are designed to be softer and more flexible, while others are thicker and firmer for lifting and contouring. Firmer gels tend to last longer.
  • Treatment area: Fillers placed in areas with less movement (like the cheeks) typically last longer than those in highly mobile areas (like the lips).
  • Patient metabolism: Some people naturally break down hyaluronic acid more quickly than others.
  • Amount of filler used: Higher volumes can sometimes provide results that last longer.
  • Lifestyle factors: Sun exposure, smoking, and stress can all accelerate skin aging and filler breakdown.

The Juvéderm Collection at Glow Aesthetic Center

Juvéderm is one of the most trusted names in dermal fillers, offering several formulations tailored to different areas of the face. All Juvéderm fillers contain hyaluronic acid, and most include lidocaine for added comfort during treatment.

Juvéderm Voluma XC

Best for: Restoring lost volume in the cheeks and midface.

Longevity: Up to 2 years in many patients.

Why it lasts longer: Voluma is formulated with a thicker gel consistency, making it durable enough to support and lift the cheeks.

Juvéderm Vollure XC

Best for: Smoothing moderate to severe facial folds, such as nasolabial folds (the lines from the nose to the corners of the mouth).

Longevity: Around 18 months.

Key benefit: Balances firmness with flexibility, so it moves naturally with facial expressions.

Juvéderm XC

Best for: Treating moderate to severe facial folds and wrinkles, including parentheses lines.

Longevity: About 12 months.

Juvéderm Ultra XC

Best for: Lip augmentation and smoothing wrinkles around the mouth.

Longevity: Roughly 6 to 12 months.

Ideal for: Patients wanting fuller lips or subtle enhancement.

Juvéderm Volbella® XC

Best for: Soft, natural lip augmentation and reducing fine lines around the mouth (perioral lines).

Longevity: Approximately 12 months.

Texture: Smooth and flexible for a natural feel.

The Restylane Collection at Glow Aesthetic Center

Like Juvéderm, Restylane offers a range of hyaluronic acid fillers designed for different cosmetic concerns. Restylane products use a unique cross-linking technology to give each filler its own consistency and staying power.

Restylane-L

Best for: Adding natural-looking volume to lips and smoothing under-eye hollows.

Longevity: About 6 to 12 months.

Restylane Lyft

Best for: Adding lift and volume to the cheeks and smoothing wrinkles. It is also FDA-approved for hand rejuvenation.

Longevity: Typically 12 to 18 months.

Firmness: Provides structural support, similar to Juvéderm Voluma.

Restylane Defyne

Best for: Treating deeper laugh lines and nasolabial folds, while maintaining natural expression.

Longevity: Up to 12 months, sometimes longer.

Restylane Refyne

Best for: Softer correction of mild to moderate laugh lines and lip enhancement.

Longevity: About 12 months.

Benefit: Designed to allow flexible movement for natural-looking expressions.

Restylane Kysse

Best for: Lip augmentation with long-lasting results.

Longevity: Up to 12 months.

Unique feature: Kysse uses XpresHAn Technology™ to allow flexible, natural lip movement while providing plumpness.

Which Filler Lasts the Longest?

When patients ask which filler lasts the longest, the answer is typically Juvéderm Voluma, which can last up to two years in the cheeks. Restylane Lyft is another long-lasting option, with results often lasting 12 to 18 months.

However, “longest-lasting” does not necessarily mean “best.” The right filler depends on the area being treated and your personal goals:

  • For cheeks and midface lift: Juvéderm Voluma or Restylane Lyft (longest duration).
  • For smile lines and folds: Juvéderm Vollure or Restylane Defyne.
  • For lips: Juvéderm Ultra, Volbella, or Restylane Kysse.
  • For under eyes: Restylane-L is often preferred for its smooth texture.

Your provider at Glow Aesthetic Center will help select the ideal filler or combination of fillers based on your unique needs.

What to Expect During Treatment

One of the best aspects of dermal filler treatments is how quick and convenient they are. Here’s what happens during a typical appointment at Glow:

  1. Consultation: Your provider will review your goals, evaluate your skin, and recommend the right filler.
  2. Preparation: The area will be cleansed, and a topical numbing cream may be applied. Most fillers also contain lidocaine for comfort.
  3. Injection: Using precise techniques, the filler is injected into the targeted areas. The procedure usually takes less than 30 minutes.
  4. Aftercare: You may experience mild swelling or bruising, which typically subsides within a few days. Most patients return to their normal activities right away.

How to Make Dermal Fillers Last Longer

While fillers are temporary, there are steps you can take to help maintain your results:

  • Protect your skin from the sun: UV rays accelerate skin aging and can break down filler more quickly.
  • Stay hydrated: Hyaluronic acid works best when your body is hydrated.
  • Maintain a healthy lifestyle: Avoid smoking and excessive alcohol, both of which can affect skin quality.
  • Follow up with maintenance treatments: Scheduling touch-ups before the filler completely dissolves can help results last longer and require less product over time.

The Glow Aesthetic Center Difference

Choosing the right provider is just as important as choosing the right filler. At Glow Aesthetic Center in Encino, our team of board-certified practitioners has extensive experience with dermal fillers and takes pride in delivering natural, beautiful results.

We use a personalized approach to ensure each patient receives the treatment best suited for their needs. Whether you want subtle lip enhancement, a midface lift, or smoother skin, we carefully select the right filler and placement technique to achieve your goals.

Book Your Dermal Fillers

So, what dermal filler lasts the longest? In most cases, Juvéderm Voluma leads the way with results lasting up to two years, followed by Restylane Lyft at 12 to 18 months. However, longevity is only part of the equation. The right filler depends on your treatment area, desired results, and personal preferences.

At Glow Aesthetic Center, we offer the full range of Juvéderm and Restylane fillers, allowing us to customize your treatment for natural, lasting results. If you’re ready to restore volume, smooth wrinkles, or enhance your features, schedule a consultation with our Encino team today.

Dermal Fillers FAQs

Do dermal fillers hurt?

Most fillers contain lidocaine, and a topical numbing cream can also be applied. Most patients describe the treatment as very tolerable.

Can fillers be dissolved if I don’t like the results?

Yes. Hyaluronic acid fillers can be reversed with an enzyme called hyaluronidase.

Are there risks with dermal fillers?

Mild side effects like swelling, bruising, and redness are common but temporary. Serious complications are rare when treatments are performed by experienced providers.

How soon will I see results?

Results are visible immediately, though minor swelling may take a few days to subside.

Can I combine fillers with other treatments?

Yes. Many patients choose to combine fillers with neurotoxin injections (like Botox or Dysport) or skin treatments for comprehensive rejuvenation.

Aesthetic treatment procedure showing a woman receiving an injection for facial enhancement, performed by a professional in blue gloves. The setting is a clean, clinical environment, emphasizing safety and expertise in cosmetic procedures.
Current Promotions

This September, Glow Aesthetic Center in Encino and Thousand Oaks is offering amazing deals for both members and non-members. Members can enjoy Botox at $10/unit and Dysport at $2.99/unit, while non-members get $11/unit for Botox and $3.50/unit for Dysport. Microneedling with exosomes is also discounted to $550 for members and $650 for non-members, plus savings of up to $300 when you buy any two fillers. – Book Now

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Saturday: Closed

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September 2025 Promotions

This September, Glow Aesthetic Center in Encino and Thousand Oaks is offering special savings for both members and non-members, with Botox as low as $10/unit and Dysport at $2.99/unit. You’ll also find discounts on microneedling with exosomes and up to $300 off when you purchase any two fillers.

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