Dermal fillers have become one of the most popular ways to enhance your appearance. However, sometimes the results don’t turn out as expected, or preferences simply change over time.
If you’ve ever wondered, “Can I get rid of my filler?” or “How does filler dissolving actually work?” — you’re not alone. At Glow Aesthetic Center, we specialize in filler correction and reversal using Hylenex® (hyaluronidase human injection), a safe and effective enzyme that dissolves unwanted hyaluronic acid-based fillers like Juvederm and Restylane.
In this comprehensive guide, we answer the top 20 questions patients ask about dissolving dermal filler with Hylenex — from how it works to what to expect before, during, and after treatment.
1. What Exactly Are Dermal Fillers?
Dermal fillers are gel-like substances, most commonly made of hyaluronic acid (HA), a natural sugar molecule found in your body that attracts and retains moisture. They are injected into specific areas of the face or body to:
- Add volume or definition
- Smooth wrinkles and folds
- Enhance features such as lips, cheeks, or chin
- Rejuvenate hands or correct under-eye hollows
Popular brands include Juvederm®, Restylane®, Belotero®, and Revanesse®, among others. Most HA-based fillers last 6 to 18 months, depending on the formula and area treated.
2. Why Would Someone Want to Dissolve Their Filler?
While fillers are generally safe and temporary, there are several reasons someone might choose to have them dissolved:
- Overfilled appearance or puffiness
- Uneven results or asymmetry
- Lumps, bumps, or migration of filler to unwanted areas
- Blocked blood vessels (vascular occlusion) — a rare but serious complication
- Allergic reaction or swelling
- Change in personal preference or aesthetic goals
In each of these cases, Hylenex can safely and quickly reverse the effects of hyaluronic acid-based filler.
3. What Is Hylenex?
Hylenex® (hyaluronidase human injection) is an enzyme that breaks down hyaluronic acid, the main ingredient in most dermal fillers. It’s made from a naturally occurring protein that dissolves HA molecules, allowing the body to reabsorb and eliminate them naturally.
Hylenex is FDA-approved and has been used in medicine for decades — long before aesthetic applications — to help with absorption of other injected drugs and to treat certain medical conditions involving HA buildup.
4. How Does Hylenex Work to Dissolve Filler?
When injected into the area where filler was previously placed, Hylenex immediately begins breaking down the bonds that hold hyaluronic acid molecules together.
Once the filler’s structure is disrupted, your body’s lymphatic system and natural metabolic processes absorb and remove the remnants.
This process usually takes 24 to 48 hours to show noticeable results, though improvements often continue over several days as swelling subsides and the skin adjusts.
5. Which Fillers Can Be Dissolved With Hylenex?
Hylenex can dissolve any filler made from hyaluronic acid, including:
- Juvederm® Collection (Ultra, Voluma, Volbella, Vollure, etc.)
- Restylane® Collection (Lyft, Kysse, Refyne, Defyne, etc.)
- Belotero Balance®
- Revanesse Versa®
- RHA® Collection of Fillers
Non-HA fillers — such as Radiesse® (calcium hydroxyapatite), Sculptra® (poly-L-lactic acid), or Bellafill® (PMMA) — cannot be dissolved with Hylenex. These fillers must naturally fade over time or require surgical removal in rare cases.
6. How Long Does It Take for Hylenex to Work?
Hylenex begins working within minutes of injection. Most patients notice visible softening of filler within the first 24 hours, with full results usually seen after 48 to 72 hours.
In some cases, mild swelling or tenderness may temporarily obscure the final results, so it’s best to evaluate your outcome a few days after treatment.
7. Will the Filler Disappear Completely?
In most cases, yes. Hylenex can completely dissolve hyaluronic acid filler when administered in the correct dosage and location. However, depending on the amount of filler and how deeply it was injected, some patients may need a second session for complete correction.
Your provider at Glow Aesthetic Center will carefully assess your results and determine if a touch-up treatment is necessary.
8. Is Filler Dissolving Safe?
Yes. When performed by a trained medical professional, filler dissolving is very safe. Hylenex has a long history of medical use and is well-tolerated by most patients.
At Glow Aesthetic Center, our injectors are highly experienced in using Hylenex precisely and conservatively to correct filler irregularities while maintaining your natural facial balance.
9. Does Hylenex Only Remove Filler, or Can It Affect Natural Hyaluronic Acid?
This is a common question. Hylenex breaks down both synthetic filler hyaluronic acid and your body’s natural HA in the injected area. However, the body quickly replaces natural HA within 24 to 48 hours, so the effect on your own tissue is temporary.
In short — Hylenex only “resets” the area. Your skin and tissues naturally restore hydration and elasticity soon after treatment.
10. How Is the Procedure Performed?
The process is simple and typically takes 15 to 30 minutes:
- Consultation and Assessment: Your injector will examine the treated area and determine where Hylenex should be placed.
- Preparation: The skin is cleansed, and a topical numbing agent may be applied for comfort.
- Injection: Small amounts of Hylenex are injected strategically using a fine needle or cannula.
- Observation: The area is gently massaged to help distribute the enzyme evenly.
You can return to your normal activities right away.
11. Does It Hurt?
Discomfort is minimal. Most patients describe a brief stinging or burning sensation at the injection site, which subsides quickly. A numbing cream or local anesthetic can be used to make the procedure even more comfortable.
12. What Side Effects Should I Expect?
After filler dissolving, it’s normal to experience:
- Mild swelling or redness
- Slight tenderness
- Temporary bruising
These effects typically resolve within 1–3 days. Applying a cold compress and avoiding strenuous activity can help minimize swelling.
Serious complications are extremely rare when the treatment is performed by a qualified medical professional.
13. How Soon Can I Get Filler Again After Dissolving?
It’s best to wait at least 7–14 days before reinjecting filler. This allows the area to fully settle, ensures all residual filler has been removed, and lets your injector work on a fresh, clean canvas for better results.
14. Can I Dissolve Just a Small Portion of Filler?
Absolutely. Many patients only want to adjust or refine their results rather than remove everything. Skilled injectors can use precise, targeted doses of Hylenex to partially dissolve filler, correcting asymmetry or overfilling while keeping the rest intact.
15. Can Hylenex Fix Filler Migration?
Yes. Filler migration, when filler moves from its intended area (for example, from lips into the surrounding skin) is one of the most common reasons people seek Hylenex. Dissolving the migrated filler restores natural contour and prevents puffiness or distortion.
16. What About Allergic Reactions?
Allergic reactions to Hylenex are rare, especially since it is a purified enzyme. If you have a history of severe allergies (particularly to bee stings or albumin-based products), let your provider know. A skin patch test can be performed prior to treatment for your safety.
17. What Results Should I Expect?
Most patients notice significant improvement in contour, smoothness, and symmetry within 48 hours.
The treated area will look more natural and balanced — closer to your original appearance or desired outcome. Any residual swelling will fade within a few days, revealing the final result.
18. Are There Any Pre- or Post-Treatment Instructions?
Before Treatment:
- Avoid alcohol and blood-thinning medications (aspirin, ibuprofen, fish oil) for 24 hours.
- Come in with a clean face and no makeup.
- Inform your provider of all medical conditions and prior filler brands.
After Treatment:
- Avoid massaging the treated area unless instructed.
- Refrain from strenuous exercise for 24 hours.
- Apply cold compresses if swelling occurs.
- Wait at least one week before getting new filler or other facial treatments.
19. How Much Does Filler Dissolving Cost?
Pricing varies depending on the amount of Hylenex used and the area treated. At Glow Aesthetic Center, your provider will evaluate your filler type and the correction needed during your consultation to give you a clear, personalized quote.
In general, dissolving small areas costs less than full-face correction, and most treatments can be completed in one session.
20. Why Choose Glow Aesthetic Center for Filler Dissolving?
At Glow Aesthetic Center, our expert injectors are highly trained in both filler placement and correction. We understand that dissolving filler requires skill, artistry, and restraint — the goal is not just to remove filler, but to restore harmony to your features.
Our patients trust us because we:
- Use authentic, FDA-approved Hylenex®.
- Perform thorough consultations to assess safety and expectations.
- Provide precision-based treatments for natural results.
- Offer post-treatment follow-ups to ensure satisfaction.
Whether you want a subtle refinement or full removal, our medical team will guide you through every step to ensure you feel comfortable, informed, and confident.
Final Thoughts
If your filler no longer suits you, you don’t have to wait months for it to fade naturally.
With Hylenex filler dissolving treatment at Glow Aesthetic Center, you can safely and effectively reverse unwanted filler and return your appearance to a balanced, natural state.
The process is quick, minimally invasive, and delivers visible results in as little as 24 to 48 hours. Our experienced practitioners specialize in both filler injections and corrections, ensuring your treatment is handled with care and precision.
If you’re considering dissolving unwanted filler, schedule your complimentary consultation at Glow Aesthetic Center today.
FAQs
Can Hylenex Be Used in Any Area Where Filler Was Placed?
Yes. Hylenex can be used to dissolve hyaluronic acid filler in areas such as the lips, cheeks, chin, under-eye region, and jawline. Your provider will assess each area to determine the safest and most effective approach.
How Do I Know If My Filler Needs Dissolving or Just Adjustment?
A consultation helps determine whether your concern is due to overfilling, product migration, asymmetry, or swelling. Some situations require partial dissolving, while others may improve with corrective filler placement.
Will Dissolving My Filler Affect Future Filler Results?
No. Once Hylenex clears the previous filler and your tissue settles, the area can be treated again with fresh filler. This often leads to more precise and natural results.
Does Hylenex Continue Working After the Procedure?
Hylenex acts quickly, but its effects continue for the next 24–48 hours as the enzyme breaks down any remaining hyaluronic acid. Your provider evaluates the final result once swelling resolves.
How Long Should I Wait Before Scheduling Other Facial Treatments?
Most patients are advised to wait at least one week before receiving additional facial procedures. This allows the area to stabilize and ensures accurate assessment of your outcome.
