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PDO Thread Face Lift vs Botox: Which Is Better?

Smiling woman with curly hair in a white shirt gently touching her face, showcasing healthy skin and a joyful expression. Ideal for beauty and skincare topics.

Facial aging is a gradual process—often starting with subtle expression lines, followed by skin laxity, loss of definition, and changes to the natural “V-shape” of the face. Fortunately, non-surgical aesthetic treatments can help address these changes without the need for invasive surgery.

Two of the most popular and effective options at Glow Aesthetic Center in Encino are PDO Thread Lifts and Botox. While both treatments aim to rejuvenate the face, they do so in different ways and are often suited to different concerns.

So which is better for lifting and reshaping the face—PDO threads or Botox? The answer depends on your goals, age, and the specific concerns you’d like to address.

What Is Botox and How Does It Work?

Botox (Botulinum toxin type A) is a neuromodulator that works by temporarily relaxing targeted facial muscles. It does this by blocking the nerve signals that cause muscles to contract. At Glow Aesthetic Center, our board-certified injectors use Botox to treat dynamic wrinkles—those caused by repeated facial movements like frowning, squinting, or smiling.

When Botox is injected into areas like the forehead, between the eyebrows (the “11s”), or around the eyes (crow’s feet), it smooths the overlying skin and helps prevent deeper lines from forming over time.

In addition to its wrinkle-relaxing powers, Botox is also used for:

  • Softening a square jawline (masseter slimming)
  • Reducing neck bands (Nefertiti lift)
  • Relaxing the trapezius muscles (Barbie Tox)
  • Treating TMJ and bruxism
  • Minimizing excessive sweating (hyperhidrosis)

Botox treatments typically take about 15–30 minutes, require no downtime, and produce noticeable results within 3–5 days. Full results appear in about two weeks and last around 3–4 months.

What Is a PDO Thread Lift and How Does It Work?

A PDO Thread Lift is a non-surgical facial rejuvenation treatment that uses absorbable sutures made of polydioxanone (PDO) to lift and tighten the skin. These threads are inserted just beneath the skin using a fine cannula and are then gently pulled to reposition sagging tissues.

As the threads dissolve over the course of four to six months, they stimulate natural collagen production, providing long-lasting support to the skin. This process—known as “controlled healing”—helps restore the skin’s firmness and elasticity, even after the threads are gone.

At Glow Aesthetic Center, NovaThreads are commonly used for:

  • Lifting the mid-face and cheeks
  • Tightening the jawline and jowls
  • Defining the neck
  • Raising sagging brows
  • Enhancing collagen in areas with volume loss

A PDO Thread Lift is often referred to as a “lunchtime lift” because the procedure typically takes under an hour, and most patients return to normal activities within a day or two.

Botox vs PDO Threads: A Side-by-Side Comparison

Let’s take a closer look at how these treatments compare across key categories:

1. Treatment Focus

Botox: Targets dynamic wrinkles caused by muscle movement. Best for smoothing fine lines and wrinkles in the upper face.

PDO Threads: Targets skin laxity and sagging. Best for lifting and tightening areas like the cheeks, jawline, and neck.

2. Mechanism of Action

Botox: Temporarily relaxes muscles to smooth the skin above.

PDO Threads: Provides immediate lift through thread placement and stimulates long-term collagen production as threads dissolve.

3. Results Timeline

Botox: Results begin in 3–5 days, with full effect in 1–2 weeks.


PDO Threads: Immediate lift is noticeable after the procedure. Collagen production enhances results over the next 1–2 months.

4. Longevity of Results

Botox: Lasts 3–4 months on average.

PDO Threads: Lifting effects can last 9–12 months, with collagen support lasting even longer.

5. Best Use Areas

Botox: Forehead lines, glabellar lines, crow’s feet, masseter slimming, neck bands.

PDO Threads: Mid-face sagging, jowls, brows, jawline, neck, and areas with skin laxity.

6. Downtime

Botox: Minimal. Most patients return to normal activities immediately.

PDO Threads: Mild swelling or bruising for 1–3 days. Full healing may take up to two weeks.

Can You Combine PDO Threads and Botox?

Yes—and in many cases, combining both treatments yields optimal results. Botox works best for expression lines, while PDO threads lift and firm sagging skin. When used together, these treatments can deliver a more complete facial rejuvenation.

For example, you might use Botox to smooth the forehead and soften crow’s feet, while PDO threads lift the mid-face or define the jawline. At Glow Aesthetic Center, our practitioners frequently use this dual approach to help patients achieve both smoothness and structure.

Which Treatment Is Right for You?

Choosing between Botox and PDO threads depends on your primary concerns:

  1. If your main goal is to reduce lines caused by facial expressions—like forehead wrinkles or crow’s feet—Botox is likely your best option.
  1. If you’re more concerned with sagging, jowls, or a loss of definition in the cheeks or jawline, PDO threads offer more visible lifting and contouring.

Age can also be a factor. Younger patients with early signs of aging may benefit from Botox for wrinkle prevention. Patients in their late 30s and beyond may see greater benefit from collagen-stimulating treatments like PDO threads to address skin laxity.

The Glow Aesthetic Center Approach

At Glow Aesthetic Center, we don’t believe in one-size-fits-all aesthetics. Every face is unique—and so is every treatment plan. Our board-certified injectors specialize in customizing Botox and PDO Thread Lifts to meet your needs, whether that’s softening fine lines or creating a more sculpted and lifted look.

Our consultations are designed to provide education, answer your questions, and recommend the right treatment or combination of treatments for your goals.

We’ll help you consider:

  • Your skin’s condition
  • Your facial anatomy and movement
  • Desired longevity of results
  • Your comfort with downtime and recovery

Final Thoughts

There’s no definitive winner in the debate between PDO Thread Lifts and Botox. Both treatments offer excellent, non-surgical solutions to common signs of aging—and they work in very different ways.

For muscle-related wrinkles, Botox is a time-tested favorite. For lifting sagging skin and restoring facial contours, PDO threads offer visible, long-lasting results. Together, they’re a powerful pair in the world of non-invasive facial rejuvenation.

If you’re curious which option—or combination—is best for you, our team at Glow Aesthetic Center is here to guide you.

Smiling woman with curly hair in a white shirt gently touching her face, showcasing healthy skin and a joyful expression. Ideal for beauty and skincare topics.
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