How Is PRF Treatment Done?

If you’re looking for a natural, effective way to refresh your appearance without synthetic fillers or invasive procedures, PRF treatment may be the right option for you. At Glow Aesthetic Center, we specialize in EZ Gel PRF—a powerful treatment that uses your own blood to stimulate collagen, restore volume, and rejuvenate your skin over time.

In this post, we’ll break down exactly how PRF treatment is done, what to expect before and after your session, and why more patients are turning to this natural solution for longer-lasting, radiant results.

What Is PRF?

PRF stands for Platelet-Rich Fibrin, a regenerative substance created from your own blood. Unlike synthetic fillers, PRF contains a high concentration of growth factors, platelets, and white blood cells—all of which work together to repair skin, stimulate collagen production, and promote natural tissue regeneration.

At Glow, we use a specialized version called EZ Gel PRF, which turns PRF into a gel-like consistency that can be injected into areas of volume loss, fine lines, or hollow skin.

EZ Gel PRF is 100% natural. It doesn’t include any synthetic additives or chemicals, which makes it an excellent choice for patients seeking a safer, more organic approach to facial rejuvenation.

Step-by-Step: How PRF Treatment Is Done

PRF treatment follows a structured yet simple process, beginning with a consultation and ending with noticeable results—without surgery, downtime, or synthetic substances.

1. Consultation and Assessment

Your experience begins with a detailed consultation at our Encino clinic. One of our experienced practitioners will assess your skin concerns, review your health history, and help you decide if PRF is right for your goals. This step ensures your treatment is safe, personalized, and built around your needs.

We’ll also discuss how many sessions might be appropriate for your goals, and which areas of your face would benefit most from EZ Gel PRF.

2. Blood Collection

Once your plan is in place, the first step in the actual treatment is a small blood draw. It’s similar to what you would experience during a routine lab test. We typically collect about 13ml of blood, which is enough to prepare your personalized PRF formula.

3. Centrifugation and Gel Creation

Your blood is then placed in a centrifuge, which spins it at a specific speed to separate its components. This process isolates the platelet-rich fibrin and plasma from the red blood cells.

The separated solution is then gently heated and cooled to create a soft, gel-like consistency. This step is what turns traditional liquid PRF into EZ Gel PRF, making it easier to inject and more effective at holding volume under the skin.

4. Injection into Targeted Areas

Once the gel is ready, our practitioner uses a fine needle or blunt-tip cannula to inject the PRF into targeted areas. Common treatment zones include:

• Under-eye hollows
• Smile lines (nasolabial folds)
• Temples
• Cheeks
• Jawline
• Chin
• Fine lines around the lips

Because EZ Gel is made from your own blood, there’s minimal risk of allergic reaction. The gel immediately adds volume while also signaling your body to produce new collagen over the next several weeks.

What Makes PRF Different From Fillers?

PRF EZ Gel is often described as a natural filler, but it works differently than traditional dermal fillers. Here’s how it stands out:

Source: PRF is 100% autologous, meaning it comes from your body. No synthetic ingredients are added.

Dual Benefits: You get an immediate volume boost and long-term skin rejuvenation.

Safety: Because there are no chemicals or additives, the risk of allergic reaction is extremely low.

Longevity: While fillers may last 6 to 12 months, PRF continues to improve your skin over time as it stimulates collagen.

Many patients at Glow use PRF either as a standalone treatment or to replace their previous filler routine with something more natural and regenerative.

What Results Can You Expect?

Results from EZ Gel PRF treatment develop in stages:

1. Immediate Volume: You’ll see some plumping and smoothing right away, especially in hollow or sunken areas.

1. Ongoing Regeneration: Over the next several weeks, your skin begins producing more collagen and elastin, which helps improve tone, texture, and firmness.

1. Long-Term Effects: While the initial volume may last around 3–6 months, the skin improvement effects can continue for up to a year or more, especially when treatments are repeated.

To get the best results, most patients benefit from a series of 3–4 treatments spaced about a month apart, with optional touch-ups every 6–12 months.

What Is Recovery Like?

Recovery is minimal. Since the treatment uses your own blood and doesn’t involve any surgery, side effects are mild and temporary. You may experience:

• Mild swelling or bruising
• Tenderness at the injection sites
• Temporary redness

These symptoms usually fade within 48–72 hours. You can return to most of your usual activities the same day, but we recommend avoiding intense exercise, alcohol, and sun exposure for at least 24 hours.

Our team will give you detailed aftercare instructions to help your skin heal and ensure the best outcome.

Who Is a Good Candidate for PRF?

PRF is safe for most healthy adults who want natural facial rejuvenation. It works well for those who:

• Prefer non-synthetic or holistic treatment options
• Are concerned about under-eye bags or facial volume loss
• Want a long-term solution that also improves skin quality
• Have mild to moderate wrinkles or sagging skin
• Are new to injectables and want a natural first step

PRF may not be ideal for people who have bleeding disorders, are pregnant, or take certain medications. Your provider will go over all necessary precautions during your consultation.

Why Choose Glow Aesthetic Center in Encino?

At Glow Aesthetic Center, we specialize in natural, results-driven esthetic care. Our board-certified providers have advanced experience with PRF and tailor every session to your facial structure and beauty goals.

Here’s what sets our Encino clinic apart:

• State-of-the-art centrifugation and PRF processing
• Personalized, thoughtful treatment plans
• Focus on natural beauty and subtle results
• Friendly, supportive care from consultation to recovery

We’re proud to offer EZ Gel PRF as part of our commitment to safe, effective, and lasting facial rejuvenation.

Book Your PRF Treatment in Encino Today

Ready to try PRF for yourself? Whether you’re just starting your skincare journey or switching from fillers, EZ Gel PRF at Glow Aesthetic Center offers a natural way to restore volume, boost collagen, and refresh your appearance.

Call us today or book a consultation online to learn more. Let us help you achieve glowing, youthful skin in a natural way.

FAQs About PRF Treatment

How is PRF different from PRP?

PRF (Platelet-Rich Fibrin) is considered the next generation of PRP (Platelet-Rich Plasma). It contains more growth factors, is spun at a slower speed to preserve more cells, and doesn’t require anticoagulants. PRF also forms a gel that allows for longer-lasting effects.

Is PRF safe?

Yes. PRF is made from your own blood, so there’s no risk of allergic reaction or rejection. At Glow, all treatments are performed by experienced providers using sterile, clinical-grade equipment.

How long does the treatment take?

The entire PRF appointment typically takes 45 minutes to 1 hour, including the blood draw, processing, and injections.

How many sessions will I need?

Most patients start with 3–4 sessions spaced 4–6 weeks apart, followed by maintenance treatments every 6–12 months to maintain results.

Will the injections hurt?

We apply a numbing cream beforehand to reduce any discomfort. Most patients report only mild pressure or pinching during the injections.

Can I combine PRF with other treatments?

Yes. PRF works well with microneedling, laser therapy, and even dermal fillers (if desired). Your provider can build a custom treatment plan to meet your goals.

When will I see results?

You’ll notice some plumping right away. Full results develop gradually over 4–12 weeks as collagen production increases.